Bryan Johnson - Complete Biohacking Protocol & Longevity Strategy

Biohacking Entrepreneur & Anti-Aging Pioneer

Bryan Johnson is an American tech entrepreneur known for founding Braintree and Kernel, who has dedicated millions of dollars to his anti-aging Blueprint Protocol. He's achieved remarkable health metrics through his scientifically rigorous approach to longevity, becoming the 'most measured man in human history' with the world's slowest speed of aging at 0.48.

Los Angeles, CA14 supplements4 protocols

Bryan Johnson's Longevity Metrics & Biomarkers

18
Biological Age
+0.48
Aging Rate/Year
47
Chronological Age
4
Active Protocols

Bryan Johnson's Complete Supplement Stack (14 Supplements)

Blueprint Longevity Mix

Comprehensive blend of vitamins, minerals, antioxidants, amino acids including CaAKG, Ashwagandha KSM66, creatine, glycine, L-theanine

1 scoop
Upon waking
Effectiveness: 9/10

Collagen Peptides

For skin elasticity, joint health, and muscle recovery

12.5-25g
Upon waking and post-workout
Effectiveness: 8/10

Metformin ER

For longevity and metabolic health

  • 24-hour glucose control with once-daily dosing
  • Reduces hepatic glucose production
1000 mg morning, 500 mg dinner
With meals
Effectiveness: 9/10

Acarbose

Prescription medication for glucose control

200 mg twice daily
With meals
Effectiveness: 9/10

EPA/DHA/DPA

Omega-3 fatty acids for brain and heart health

800 mg twice daily
Morning and dinner
Effectiveness: 8/10

NAC

Antioxidant and liver support

  • Increases glutathione production
  • Supports respiratory health and reduces mucus
1800 mg
With dinner
Effectiveness: 8/10

Melatonin

Sleep optimization

300 mcg
Before bed
Effectiveness: 7/10

Garlic (Kyolic)

Cardiovascular health

2.4g total (1.2g twice daily)
Morning and with dinner

NR or NMN

NAD+ precursors for cellular energy and DNA repair

  • May improve insulin sensitivity
  • Potential cardiovascular benefits
500mg NMN or 450mg NR
Morning
Effectiveness: 8/10

ProButyrate

Gut health support

600mg
Morning

Heme Iron + Vitamin C

Enhanced iron absorption for energy levels and immune support

  • Improves iron status and increases serum ferritin
  • Reduces fatigue and increases energy levels
10mg iron + 250mg vitamin C
Morning after UV light exposure
Effectiveness: 8/10

Multivitamin

Contains Ubiquinol, Fisetin, Genistein, Luteolin, B vitamins

3 capsules
Morning with 20-pill stack
Effectiveness: 9/10

Omega-3 (EPA/DHA/DPA)

High-dose omega-3s for brain and cardiovascular health

  • Reduces triglyceride levels
  • Supports heart health and reduces cardiovascular disease risk
800mg
Morning and dinner
Effectiveness: 9/10

N-Acetylcysteine + Ginger + Curcumin

Anti-inflammatory and antioxidant support

  • Reduces respiratory inflammation and mucus production
  • Provides potent antioxidant protection
3 capsules (1800mg NAC total)
Morning and dinner
Effectiveness: 8/10

Bryan Johnson's Biohacking Protocols

Blueprint Protocol

Comprehensive anti-aging regimen based on rigorous scientific evidence, data-driven decision making, and systematic optimization of all health markers

Category:longevity
Duration:N/A
Difficulty:advanced
Cost:medium
Effectiveness Rate: 95%

Sleep Optimization Protocol

Achieved 8 months of perfect 100% sleep scores through consistent bedtime, sleep environment optimization, and strict wind-down routines

Category:sleep
Duration:N/A
Difficulty:intermediate
Cost:medium
Effectiveness Rate: 100%

Blueprint Exercise Protocol

Daily 60-90 minute workout with 25+ exercises focusing on cardiovascular zones 2-4 for 4.5 hours and zone 5 for 1.5 hours weekly

Category:exercise
Duration:N/A
Difficulty:intermediate
Cost:medium
Effectiveness Rate: 92%

Plant-Based Nutrient Density Protocol

Plant-based diet with 70+ lbs of vegetables monthly, early time-restricted feeding (6-11am eating window), and 2,250 calories daily

Category:nutrition
Duration:N/A
Difficulty:advanced
Cost:medium
Effectiveness Rate: 90%

Bryan Johnson's Daily Biohacking Routine

Wake Time:N/A
Bed Time:22:00:00

Daily Schedule:

MorningBlueprint Longevity Mix + supplements
Post-wakeLight therapy
Morning1-hour workout
11:00Super Veggie meal + supplements
AfternoonNutty Pudding
EveningThird meal
21:001-hour wind down
Before bedMelatonin

Bryan Johnson's Diet & Nutrition Protocol

Blueprint Diet

Vegan diet (except collagen) with 3 meals: Super Veggie, Nutty Pudding, and variable third meal

Meal Timing

16-18 hour daily fast

Diet Type

plant-based

Bryan Johnson's Exercise & Fitness Protocols

Blueprint Fitness

Type:mixed
Frequency:Daily
Duration:60 minutes

Frequently Asked Questions About Bryan Johnson

What is Bryan Johnson's biological age?

Bryan Johnson's biological age is 18 years, which is 29 years younger than their chronological age of 47.

How many supplements does Bryan Johnson take?

Bryan Johnson takes 14 different supplements daily as part of their longevity protocol. Key supplements include Blueprint Longevity Mix, Collagen Peptides, Metformin ER, and more.

What diet does Bryan Johnson follow?

Bryan Johnson follows a Blueprint Diet diet protocol with 16-18 hour daily fast. Vegan diet (except collagen) with 3 meals: Super Veggie, Nutty Pudding, and variable third meal

What is Bryan Johnson's exercise routine?

Bryan Johnson follows 1 distinct exercise protocol. Their primary protocol is Blueprint Fitness, performed Daily.