Magnesium Threonate Supplement Guide: Benefits, Dosage & Reviews
Enhances cognitive function, memory, and brain health by increasing magnesium levels in the brain
Magnesium L-threonate is a specially formulated form of magnesium that can cross the blood-brain barrier and increase magnesium levels directly in the brain. It is designed to support cognitive health, memory, focus, and overall brain function.
Magnesium Threonate Key Metrics & Safety Profile
Research Quality & Regulatory Status
FDA & Regulatory Status
FDA reviewed GRAS dossier GRN No 499 in 2014 for use in food and food supplements as magnesium source without raising questions
Where to Buy Magnesium Threonate
Compare prices from trusted brands.
💡 Pro Tip: Start with the lowest effective dose and monitor your response. Quality varies between brands - choose reputable manufacturers only.
Magnesium Threonate Dosage & Timing Recommendations
Recommended Dosage
1.5-3g daily (providing approximately 124-250mg elemental magnesium)
Optimal Timing
Divided into two doses, can be taken with or without food
Important Dosage Notes
Always start with the lowest effective dose and gradually increase as needed. Individual responses vary significantly based on body weight, metabolism, and health status.
Magnesium Threonate Benefits & Effects
- ✓Enhanced memory and learning
- ✓Improved cognitive function
- ✓Better sleep quality
- ✓Reduced anxiety and stress
- ✓Increased synaptic plasticity
- ✓Protection against age-related cognitive decline
- ✓Improved executive function
Magnesium Threonate Side Effects & Safety Considerations
While Magnesium Threonate is generally considered safe with a safety score of 7/10, some individuals may experience the following side effects:
- ⚠Digestive discomfort
- ⚠Bloating
- ⚠Gas
- ⚠Upset stomach
- ⚠Drowsiness
- ⚠Headaches
- ⚠Nausea
- ⚠Loose stools
Magnesium Threonate Drug Interactions & Contraindications
Magnesium Threonate may interact with certain medications or conditions. Consult your healthcare provider if you are taking:
- ⚡Blood pressure medications (calcium channel blockers)
- ⚡Antibiotics (tetracyclines, quinolones)
- ⚡Sleep aids and sedatives
- ⚡Loop diuretics
- ⚡Thiazide diuretics
- ⚡Potassium-sparing diuretics
- ⚡Muscle relaxants
- ⚡Penicillamine
- ⚡Corticosteroids
Magnesium Threonate Reviews from Verified Biohackers
Neuroscientist and Professor at Stanford University School of Medicine
140mg
30-60 minutes before bed
9/10
“Crosses blood-brain barrier for sleep and cognitive support”
Human Biologist, Biohacker, and Longevity Expert
200-400 mg
Evening
9/10
“Uses well-absorbed forms to aid sleep, muscle relaxation, and mental calmness”
Author, Entrepreneur, and Investor
144mg
Daily
8/10
“Sleep optimization and brain health”
Longevity Biohacker and Former Network Security Professional
1000mg
Bedtime
8/10
“Sleep support and brain health”
Frequently Asked Questions About Magnesium Threonate
What is Magnesium Threonate?
Magnesium L-threonate is a specially formulated form of magnesium that can cross the blood-brain barrier and increase magnesium levels directly in the brain. It is designed to support cognitive health, memory, focus, and overall brain function.
Is Magnesium Threonate safe?
Magnesium Threonate has a safety score of 7/10 based on available research and user reports.As with any supplement, individual responses may vary. Always start with the lowest effective dose and monitor for any adverse reactions.
How effective is Magnesium Threonate?
Magnesium Threonate has an effectiveness score of 75% with moderate evidence supporting its use. Effectiveness can vary significantly between individuals based on genetics, lifestyle, and health status.
Can I take Magnesium Threonate with other supplements?
Magnesium Threonate may interact with certain medications and supplements. Known interactions include: Blood pressure medications (calcium channel blockers), Antibiotics (tetracyclines, quinolones), Sleep aids and sedatives, Loop diuretics, Thiazide diuretics, Potassium-sparing diuretics, Muscle relaxants, Penicillamine, Corticosteroids. Consult with a healthcare provider before combining supplements.