Magnesium L-Threonate Supplement Guide: Benefits, Dosage & Reviews

Enhances cognitive function, memory, and brain health by increasing magnesium levels in the brain.

Magnesium L-threonate is a patented form of magnesium specifically designed to cross the blood-brain barrier and increase brain magnesium levels. It was developed to enhance cognitive function, memory, and synaptic plasticity by elevating neuronal intracellular magnesium concentrations.

cognitionAverage Cost: $15/month

Magnesium L-Threonate Key Metrics & Safety Profile

8/10
Safety Score
75%
Effectiveness
moderate
Evidence Level
low
Cost Level

Research Quality & Regulatory Status

FDA & Regulatory Status

FDA Approved
No
StatusGRAS
Approval Date5/15/2014

FDA reviewed GRAS dossier (GRN No 499) in 2014 for use in food and food supplements as magnesium source without raising questions

Where to Buy Magnesium L-Threonate

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💡 Pro Tip: Start with the lowest effective dose and monitor your response. Quality varies between brands - choose reputable manufacturers only.

Magnesium L-Threonate Dosage & Timing Recommendations

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Recommended Dosage

1.5-3g daily (providing approximately 125-250mg elemental magnesium)

Optimal Timing

Divided doses with meals, preferably with breakfast and dinner

Important Dosage Notes

Always start with the lowest effective dose and gradually increase as needed. Individual responses vary significantly based on body weight, metabolism, and health status.

Magnesium L-Threonate Benefits & Effects

  • Enhanced memory and learning
  • Improved cognitive function
  • Better synaptic plasticity
  • Supports brain health and neuroprotection
  • May reduce cognitive decline
  • Improved sleep quality
  • Reduced anxiety and stress
  • Enhanced focus and mental clarity

Magnesium L-Threonate Side Effects & Safety Considerations

While Magnesium L-Threonate is generally considered safe with a safety score of 8/10, some individuals may experience the following side effects:

  • Digestive discomfort
  • Bloating and gas
  • Drowsiness or sedation
  • Headaches
  • Nausea
  • Upset stomach
  • Diarrhea (with high doses)
  • Fatigue

Magnesium L-Threonate Drug Interactions & Contraindications

Magnesium L-Threonate may interact with certain medications or conditions. Consult your healthcare provider if you are taking:

  • Blood pressure medications (calcium channel blockers)
  • Antibiotics (tetracyclines, quinolones)
  • Sleep aids and sedatives
  • Diuretics
  • Muscle relaxants
  • Bisphosphonates
  • Iron supplements (reduced absorption)

Frequently Asked Questions About Magnesium L-Threonate

What is Magnesium L-Threonate?

Magnesium L-threonate is a patented form of magnesium specifically designed to cross the blood-brain barrier and increase brain magnesium levels. It was developed to enhance cognitive function, memory, and synaptic plasticity by elevating neuronal intracellular magnesium concentrations.

Is Magnesium L-Threonate safe?

Magnesium L-Threonate has a safety score of 8/10 based on available research and user reports.As with any supplement, individual responses may vary. Always start with the lowest effective dose and monitor for any adverse reactions.

How effective is Magnesium L-Threonate?

Magnesium L-Threonate has an effectiveness score of 75% with moderate evidence supporting its use. Effectiveness can vary significantly between individuals based on genetics, lifestyle, and health status.

Can I take Magnesium L-Threonate with other supplements?

Magnesium L-Threonate may interact with certain medications and supplements. Known interactions include: Blood pressure medications (calcium channel blockers), Antibiotics (tetracyclines, quinolones), Sleep aids and sedatives, Diuretics, Muscle relaxants, Bisphosphonates, Iron supplements (reduced absorption). Consult with a healthcare provider before combining supplements.