Omega-3 Supplement Guide: Benefits, Dosage & Reviews

To support cardiovascular health, brain function, reduce inflammation, and provide essential fatty acids the body cannot produce adequately.

Omega-3 fatty acids are essential polyunsaturated fatty acids, primarily EPA, DHA, and ALA, that play crucial roles in brain function, heart health, and inflammation reduction. These fatty acids must be obtained through diet or supplementation as the body cannot produce them in sufficient quantities.

nutritionFDA ApprovedAverage Cost: $30/monthUsed by 7 biohackers

Omega-3 Key Metrics & Safety Profile

8/10
Safety Score
85%
Effectiveness
strong
Evidence Level
medium
Cost Level

Research Quality & Regulatory Status

FDA & Regulatory Status

FDA Approved
Yes
StatusGRAS
Approval Date2/12/2004

Multiple GRAS notices approved for algal-derived DHA oils. FDA affirmed GRAS status for menhaden oil with limit of 3g/day combined EPA and DHA. Qualified health claim approved for EPA and DHA reducing coronary heart disease risk.

Where to Buy Omega-3

Compare prices from trusted brands.

💡 Pro Tip: Start with the lowest effective dose and monitor your response. Quality varies between brands - choose reputable manufacturers only.

Omega-3 Dosage & Timing Recommendations

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Recommended Dosage

1-3g daily of combined EPA and DHA

Optimal Timing

With meals to maximize absorption and reduce gastrointestinal side effects

Important Dosage Notes

Always start with the lowest effective dose and gradually increase as needed. Individual responses vary significantly based on body weight, metabolism, and health status.

Omega-3 Benefits & Effects

  • Supports cardiovascular health and reduces heart disease risk
  • Improves brain function and cognitive performance
  • Reduces inflammation throughout the body
  • Supports eye health and vision
  • May reduce symptoms of depression and anxiety
  • Supports healthy pregnancy and fetal development
  • May reduce joint pain and stiffness
  • Supports healthy skin and hair
  • May improve sleep quality
  • Supports immune system function

Omega-3 Side Effects & Safety Considerations

While Omega-3 is generally considered safe with a safety score of 8/10, some individuals may experience the following side effects:

  • Fishy aftertaste or burping
  • Gastrointestinal upset or nausea
  • Diarrhea
  • Acid reflux or heartburn
  • Bad breath
  • Headache
  • Odoriferous sweat
  • Potential increased bleeding time at high doses

Omega-3 Drug Interactions & Contraindications

Omega-3 may interact with certain medications or conditions. Consult your healthcare provider if you are taking:

  • Warfarin and other anticoagulants - may increase bleeding risk
  • Aspirin - may increase bleeding risk when combined
  • Blood pressure medications - may enhance hypotensive effects
  • Diabetes medications - may affect blood sugar control
  • Immunosuppressive drugs - may reduce immune function at high doses

Omega-3 Reviews from Verified Biohackers

RP

PhD in Biomedical Science, Health Optimization Expert

Dosage:

2g EPA/DHA daily

Timing:

1g with breakfast, 1g in evening

Rating:

10/10

Maintains omega-3 index around 10-12%, anti-inflammatory
AH

Neuroscientist and Professor at Stanford University School of Medicine

Dosage:

2000-3000mg EPA

Timing:

With meals

Rating:

9/10

Anti-inflammatory, mood support, cognitive health
PA
Peter AttiaVerified

Longevity-focused physician and author

Dosage:

4 capsules (2g EPA, 1.5g DHA)

Timing:

Morning

Rating:

9/10

High-quality omega-3 for cardiovascular and cognitive health
LH

Professional Big Wave Surfer, Fitness Expert, and Longevity Pioneer

Dosage:

As directed

Timing:

Daily

Rating:

9/10

Essential for heart health and reducing inflammation
MH
Mark HymanVerified

Physician, Author, and Functional Medicine Expert

Dosage:

2 softgels

Timing:

Daily with meal

Rating:

9/10

Wild Alaskan salmon oil for heart, cardiovascular, skin and eye health
GB
Gary BreckaVerified

Human Biologist, Biohacker, and Longevity Expert

Dosage:

1-3 grams EPA/DHA

Timing:

Morning with DHEA

Rating:

9/10

Taken daily to reduce inflammation, benefit heart health, and balance hormones
SL
Siim LandVerified

Longevity Expert, Biohacker, and Best-Selling Author

Dosage:

2-3g

Timing:

Daily

Rating:

8/10

Brain health, cardiovascular protection, inflammation reduction

Frequently Asked Questions About Omega-3

What is Omega-3?

Omega-3 fatty acids are essential polyunsaturated fatty acids, primarily EPA, DHA, and ALA, that play crucial roles in brain function, heart health, and inflammation reduction. These fatty acids must be obtained through diet or supplementation as the body cannot produce them in sufficient quantities.

Is Omega-3 safe?

Omega-3 has a safety score of 8/10 based on available research and user reports. This supplement is FDA approved.As with any supplement, individual responses may vary. Always start with the lowest effective dose and monitor for any adverse reactions.

How effective is Omega-3?

Omega-3 has an effectiveness score of 85% with strong evidence supporting its use. Effectiveness can vary significantly between individuals based on genetics, lifestyle, and health status.

Can I take Omega-3 with other supplements?

Omega-3 may interact with certain medications and supplements. Known interactions include: Warfarin and other anticoagulants - may increase bleeding risk, Aspirin - may increase bleeding risk when combined, Blood pressure medications - may enhance hypotensive effects, Diabetes medications - may affect blood sugar control, Immunosuppressive drugs - may reduce immune function at high doses. Consult with a healthcare provider before combining supplements.