Nicotinamide Mononucleotide Supplement Guide: Benefits, Dosage & Reviews
To increase NAD+ levels and support cellular energy production and healthy aging processes.
Nicotinamide Mononucleotide (NMN) is a precursor to NAD+, an essential coenzyme involved in cellular energy production, DNA repair, and aging processes. NMN supplementation aims to increase NAD+ levels in cells, potentially supporting healthy aging and metabolic function.
Nicotinamide Mononucleotide Key Metrics & Safety Profile
Research Quality & Regulatory Status
FDA & Regulatory Status
FDA declared NMN prohibited as a dietary supplement in November 2022 due to prior drug investigation status, though this ruling is being challenged
Where to Buy Nicotinamide Mononucleotide
Compare prices from trusted brands.
💡 Pro Tip: Start with the lowest effective dose and monitor your response. Quality varies between brands - choose reputable manufacturers only.
Nicotinamide Mononucleotide Dosage & Timing Recommendations
Recommended Dosage
250-1000mg daily
Optimal Timing
With breakfast or morning meal
Important Dosage Notes
Always start with the lowest effective dose and gradually increase as needed. Individual responses vary significantly based on body weight, metabolism, and health status.
Nicotinamide Mononucleotide Benefits & Effects
- ✓Increases NAD+ levels in blood and tissues
- ✓Improves muscle insulin sensitivity
- ✓Enhances aerobic exercise capacity
- ✓Supports cardiovascular health
- ✓May improve muscle strength and physical performance
- ✓Supports cellular energy metabolism
- ✓May help with age-related physiological decline
- ✓Supports DNA repair mechanisms
Nicotinamide Mononucleotide Side Effects & Safety Considerations
While Nicotinamide Mononucleotide is generally considered safe with a safety score of 8/10, some individuals may experience the following side effects:
- ⚠Generally well-tolerated with minimal side effects reported
- ⚠Mild gastrointestinal discomfort (rare)
- ⚠No serious adverse events reported in clinical trials
Nicotinamide Mononucleotide Drug Interactions & Contraindications
Nicotinamide Mononucleotide may interact with certain medications or conditions. Consult your healthcare provider if you are taking:
- ⚡May interact with diabetes medications due to effects on insulin sensitivity
- ⚡Potential interactions with blood pressure medications
- ⚡Should avoid concurrent use with high-dose niacin supplements
Nicotinamide Mononucleotide Reviews from Verified Biohackers
Professor of Genetics at Harvard Medical School and Longevity Researcher
1000mg
Morning with yogurt
9/10
“Boosts NAD+ levels for cellular energy and DNA repair”
Frequently Asked Questions About Nicotinamide Mononucleotide
What is Nicotinamide Mononucleotide?
Nicotinamide Mononucleotide (NMN) is a precursor to NAD+, an essential coenzyme involved in cellular energy production, DNA repair, and aging processes. NMN supplementation aims to increase NAD+ levels in cells, potentially supporting healthy aging and metabolic function.
Is Nicotinamide Mononucleotide safe?
Nicotinamide Mononucleotide has a safety score of 8/10 based on available research and user reports.As with any supplement, individual responses may vary. Always start with the lowest effective dose and monitor for any adverse reactions.
How effective is Nicotinamide Mononucleotide?
Nicotinamide Mononucleotide has an effectiveness score of 72% with moderate evidence supporting its use. Effectiveness can vary significantly between individuals based on genetics, lifestyle, and health status.
Can I take Nicotinamide Mononucleotide with other supplements?
Nicotinamide Mononucleotide may interact with certain medications and supplements. Known interactions include: May interact with diabetes medications due to effects on insulin sensitivity, Potential interactions with blood pressure medications, Should avoid concurrent use with high-dose niacin supplements. Consult with a healthcare provider before combining supplements.