Fisetin Supplement Guide: Benefits, Dosage & Reviews

Primary use is as an anti-aging compound that may help clear senescent cells and support cellular health.

Fisetin is a naturally occurring flavonoid found in fruits like strawberries, apples, and persimmons that has gained attention for its potential senolytic properties and ability to combat cellular aging. It acts as a potent antioxidant with anti-inflammatory, neuroprotective, and anti-cancer effects through multiple cellular pathways.

longevityAverage Cost: $60/monthUsed by 1 biohacker

Fisetin Key Metrics & Safety Profile

8/10
Safety Score
65%
Effectiveness
moderate
Evidence Level
high
Cost Level

Research Quality & Regulatory Status

FDA & Regulatory Status

FDA Approved
No
StatusNot Approved

Classified as a dietary supplement, not regulated as a drug by FDA

Where to Buy Fisetin

Compare prices from trusted brands.

💡 Pro Tip: Start with the lowest effective dose and monitor your response. Quality varies between brands - choose reputable manufacturers only.

Fisetin Dosage & Timing Recommendations

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Recommended Dosage

100-500mg daily for general use, with higher doses of 1000-1500mg used for senolytic 'pulse' protocols

Optimal Timing

With meals containing healthy fats to improve absorption

Important Dosage Notes

Always start with the lowest effective dose and gradually increase as needed. Individual responses vary significantly based on body weight, metabolism, and health status.

Fisetin Benefits & Effects

  • Anti-aging and cellular senescence reduction
  • Neuroprotective effects for brain health
  • Antioxidant protection against oxidative stress
  • Anti-inflammatory properties
  • Potential anticancer effects
  • Cardiovascular health support
  • Blood sugar regulation
  • Cognitive function enhancement
  • Skin health and UV protection

Fisetin Side Effects & Safety Considerations

While Fisetin is generally considered safe with a safety score of 8/10, some individuals may experience the following side effects:

  • Mild stomach upset
  • Headache
  • Generally well tolerated with minimal reported adverse effects

Fisetin Drug Interactions & Contraindications

Fisetin may interact with certain medications or conditions. Consult your healthcare provider if you are taking:

  • May interact with medications metabolized by the liver
  • Potential interactions with blood thinners
  • Should be used cautiously with other supplements

Fisetin Reviews from Verified Biohackers

DS

Professor of Genetics at Harvard Medical School and Longevity Researcher

Dosage:

500mg

Timing:

Morning

Rating:

7/10

Senolytic compound to eliminate senescent cells

Frequently Asked Questions About Fisetin

What is Fisetin?

Fisetin is a naturally occurring flavonoid found in fruits like strawberries, apples, and persimmons that has gained attention for its potential senolytic properties and ability to combat cellular aging. It acts as a potent antioxidant with anti-inflammatory, neuroprotective, and anti-cancer effects through multiple cellular pathways.

Is Fisetin safe?

Fisetin has a safety score of 8/10 based on available research and user reports.As with any supplement, individual responses may vary. Always start with the lowest effective dose and monitor for any adverse reactions.

How effective is Fisetin?

Fisetin has an effectiveness score of 65% with moderate evidence supporting its use. Effectiveness can vary significantly between individuals based on genetics, lifestyle, and health status.

Can I take Fisetin with other supplements?

Fisetin may interact with certain medications and supplements. Known interactions include: May interact with medications metabolized by the liver, Potential interactions with blood thinners, Should be used cautiously with other supplements. Consult with a healthcare provider before combining supplements.