Apigenin Supplement Guide: Benefits, Dosage & Reviews

Supports healthy aging, sleep quality, and cellular longevity through anti-inflammatory effects and NAD preservation

Apigenin is a plant flavone found in chamomile, parsley, and celery that supports healthy aging, sleep quality, and cellular longevity through anti-inflammatory and NAD-boosting mechanisms. It promotes cellular apoptosis while reducing chronic inflammation and preserving NAD levels for optimal cellular function.

longevityAverage Cost: $60/monthUsed by 1 biohacker

Apigenin Key Metrics & Safety Profile

7/10
Safety Score
70%
Effectiveness
moderate
Evidence Level
high
Cost Level

Research Quality & Regulatory Status

FDA & Regulatory Status

FDA Approved
No
StatusNot Approved

Not labeled as Generally Recognized as Safe (GRAS) by FDA, but abundant in natural food sources

Where to Buy Apigenin

Compare prices from trusted brands.

💡 Pro Tip: Start with the lowest effective dose and monitor your response. Quality varies between brands - choose reputable manufacturers only.

Apigenin Dosage & Timing Recommendations

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Recommended Dosage

50-100mg daily

Optimal Timing

30-60 minutes before bed for sleep support, or with meals for general health benefits

Important Dosage Notes

Always start with the lowest effective dose and gradually increase as needed. Individual responses vary significantly based on body weight, metabolism, and health status.

Apigenin Benefits & Effects

  • Reduced inflammation
  • Enhanced NAD levels
  • Improved sleep quality
  • Reduced anxiety
  • Neuroprotection
  • Cardiovascular support
  • Antioxidant effects
  • Cellular apoptosis promotion
  • Anti-aging support
  • Mood enhancement

Apigenin Side Effects & Safety Considerations

While Apigenin is generally considered safe with a safety score of 7/10, some individuals may experience the following side effects:

  • May interact with blood thinners
  • Potential blood pressure drops
  • Risk of hypoglycemia with diabetes medications
  • Sedative effects
  • Hormonal interference

Apigenin Drug Interactions & Contraindications

Apigenin may interact with certain medications or conditions. Consult your healthcare provider if you are taking:

  • Blood-thinning medications (warfarin)
  • Blood pressure medications
  • Diabetes medications
  • Sedatives and alcohol
  • Benzodiazepines
  • Hormonal therapies
  • CYP1A2 substrates
  • CYP2C9 substrates
  • CYP3A4 substrates

Apigenin Reviews from Verified Biohackers

AH

Neuroscientist and Professor at Stanford University School of Medicine

Dosage:

50mg

Timing:

30-60 minutes before bed

Rating:

8/10

Chamomile extract for sleep onset and relaxation

Frequently Asked Questions About Apigenin

What is Apigenin?

Apigenin is a plant flavone found in chamomile, parsley, and celery that supports healthy aging, sleep quality, and cellular longevity through anti-inflammatory and NAD-boosting mechanisms. It promotes cellular apoptosis while reducing chronic inflammation and preserving NAD levels for optimal cellular function.

Is Apigenin safe?

Apigenin has a safety score of 7/10 based on available research and user reports.As with any supplement, individual responses may vary. Always start with the lowest effective dose and monitor for any adverse reactions.

How effective is Apigenin?

Apigenin has an effectiveness score of 70% with moderate evidence supporting its use. Effectiveness can vary significantly between individuals based on genetics, lifestyle, and health status.

Can I take Apigenin with other supplements?

Apigenin may interact with certain medications and supplements. Known interactions include: Blood-thinning medications (warfarin), Blood pressure medications, Diabetes medications, Sedatives and alcohol, Benzodiazepines, Hormonal therapies, CYP1A2 substrates, CYP2C9 substrates, CYP3A4 substrates. Consult with a healthcare provider before combining supplements.