Vitamin D3 + K2 Supplement Guide: Benefits, Dosage & Reviews
Supports bone health, cardiovascular health, and proper calcium utilization in the body.
A fat-soluble vitamin combination supplement containing vitamin D3 (cholecalciferol) and vitamin K2 (menaquinone-7). These vitamins work synergistically to support bone health, cardiovascular health, and calcium metabolism.
Vitamin D3 + K2 Key Metrics & Safety Profile
Research Quality & Regulatory Status
FDA & Regulatory Status
Both vitamin D3 and K2 are generally recognized as safe. No tolerable upper intake level set due to lack of adverse effects in healthy individuals.
Where to Buy Vitamin D3 + K2
Compare prices from trusted brands.
💡 Pro Tip: Start with the lowest effective dose and monitor your response. Quality varies between brands - choose reputable manufacturers only.
Vitamin D3 + K2 Dosage & Timing Recommendations
Recommended Dosage
1000-4000 IU vitamin D3 + 100-200 mcg vitamin K2 daily
Optimal Timing
With food (preferably with fats)
Important Dosage Notes
Always start with the lowest effective dose and gradually increase as needed. Individual responses vary significantly based on body weight, metabolism, and health status.
Vitamin D3 + K2 Benefits & Effects
- ✓Improved bone mineral density
- ✓Enhanced calcium absorption and utilization
- ✓Reduced vascular calcification
- ✓Better cardiovascular health
- ✓Reduced fracture risk
- ✓Improved immune function
- ✓Synergistic bone and heart protection
Vitamin D3 + K2 Side Effects & Safety Considerations
While Vitamin D3 + K2 is generally considered safe with a safety score of 8/10, some individuals may experience the following side effects:
- ⚠Weakness
- ⚠Fatigue
- ⚠Sleepiness
- ⚠Headache
- ⚠Loss of appetite
- ⚠Dry mouth
- ⚠Metallic taste
- ⚠Nausea and vomiting
- ⚠Hypercalcemia (with excessive doses)
Vitamin D3 + K2 Drug Interactions & Contraindications
Vitamin D3 + K2 may interact with certain medications or conditions. Consult your healthcare provider if you are taking:
- ⚡Warfarin and blood thinners
- ⚡Thiazide diuretics
- ⚡Calcium channel blockers
- ⚡Digoxin
- ⚡Thiazide and thiazide-like diuretics
- ⚡Magnesium supplements
- ⚡Calcium supplements
Vitamin D3 + K2 Reviews from Verified Biohackers
Human Biologist, Biohacker, and Longevity Expert
5,000 IU D3 with 80 mcg K2
Daily with fat
9/10
“To boost immunity, regulate hormones, and protect bone and heart health”
Frequently Asked Questions About Vitamin D3 + K2
What is Vitamin D3 + K2?
A fat-soluble vitamin combination supplement containing vitamin D3 (cholecalciferol) and vitamin K2 (menaquinone-7). These vitamins work synergistically to support bone health, cardiovascular health, and calcium metabolism.
Is Vitamin D3 + K2 safe?
Vitamin D3 + K2 has a safety score of 8/10 based on available research and user reports.As with any supplement, individual responses may vary. Always start with the lowest effective dose and monitor for any adverse reactions.
How effective is Vitamin D3 + K2?
Vitamin D3 + K2 has an effectiveness score of 85% with strong evidence supporting its use. Effectiveness can vary significantly between individuals based on genetics, lifestyle, and health status.
Can I take Vitamin D3 + K2 with other supplements?
Vitamin D3 + K2 may interact with certain medications and supplements. Known interactions include: Warfarin and blood thinners, Thiazide diuretics, Calcium channel blockers, Digoxin, Thiazide and thiazide-like diuretics, Magnesium supplements, Calcium supplements. Consult with a healthcare provider before combining supplements.